You must know Krombral, the Giants' language, in order to complete this quest.
Starting the Quest
Approach the ravine in Lavastorm that leads to the entry to Maiden's Gulch and speak to Sebir the Historian ( -168, -10, -546 ) Copy/waypoint -168, -10, -546 who tells you about the sage who needs to be rescued.
Kill the Drakota Inquisitor and Vyr'drais the Vicious (51^^^ Heroic) with 2 adds, and then hail The Sage of Ages on the platform behind him to start the quest.
Steps
Once you've started the quest with the Sage, travel to the bottom of Solusek's Eye (sublevel 6, where translucent paths wind over the lava) and enter Nagafen's Lair. ( -202, -617, -198 ) Copy/waypoint -202, -617, -198.
Note: to get to Nagafen's Lair you will need to take a lift to the third floor ( -325, -595, 187 ) Copy/waypoint -325, -595, 187 in the Giant Apartments. It may appear that you can only travel up to the second floor, so to get to the third floor open the door once you arrive at the second floor and hit the "up" option on the triangular button just inside the door. Then hustle back onto the lift since there is a short delay before the lift moves up to the third floor. There will be a one-way ledge at ( -103, -614, -292 ) Copy/waypoint -103, -614, -292 followed by the Oratorium of Thyr. (This instance is not required for the quest, but must be completed unless you have the assistance of someone with access to the deserted version.)
Speak to Majordomo Inferinus who tells you that you need to learn the Elder Dragon language to be able to speak with Lord Nagafen.
Return to The Sage of Ages in Antonica on the top floor of the Tower of the Oracles ( -1030, 14, -618 ) Copy/waypoint -1030, 14, -618. If he disappears or is not there, leave and re-enter the tower again. He tells you that you need to find 26 translated runes of Elder Dragon to learn the language.
Gather the 26 runes: If this is your first character (on a given account) completing this quest, you must gather the 26 runes from their locations in the world, as listed below.
If you have already completed this quest on at least one character, you can transfer the heirloom tablet of the runes from completing the quest (which can be re-purchased at the Shady Swashbuckler on the Nektulos docks) through the shared bank. Examining this tablet will satisfy this step.
Once you have all 26, speak to The Sage of Ages again in Antonica at ( -1030, 14, -618 ) Copy/waypoint -1030, 14, -618 for your reward.
Locations of the runes
The runes are scattered all over the Shattered Lands (the zones originally available when the game launched).
To see or close the full list of rune locations, click:
On a bookshelf across from the door. ( -127, -32, -140 ) Copy/waypoint -127, -32, -140 (You get access by clicking on a grate in the floor at ( 5, -26, -121 ) Copy/waypoint 5, -26, -121 on the second level down in Stormhold.)
Go inside the tent behind Merchant Murgina and look up. The scroll is standing on its end next to the center pole up top. ( -149, 14, 187 ) Copy/waypoint -148.85, 13.72, 186.77
In the top of the rearmost right-hand tower (as you enter), a chest on the second floor under the stairs. ( 701, 10, -735 ) Copy/waypoint 701, 10, -735
The scroll on a table on the left side of room. ( -317, -516, 127 ) Copy/waypoint -317, -516, 127
To get to the Glassworker's room, go to Sublevel 5 and go to the elevator at ( -313, -512, 186 ) Copy/waypoint -313.09, -512.43, 186.38 and go up one level, and then exit.
On level 1, on a table. ( -48, 594, 286 ) Copy/waypoint -48, 594, 286
Sissthra and Rett Runes: You may need to complete the access quest Summoning the Creator in order to unlock the door leading to the lower levels.
Voth Rune: You will either have to complete the access quest Entrance into the Obelisk or use the Feerrott zone-in which puts you just inside the Obelisk.
Note: completing the access quests may now be unnecessary if the zones are gray to your toon.