Collect 12 petals of Karana's Begonia. These appear to spawn near trees. They are a yellow flower, some near the docks, some towards the wasp nest, some over towards the seamyst fae, some on the fae isle itself and there are a couple at the Runnyeye Ward.
Head to the Lazy Drain ( -183, -5, -256 ) Copy/waypoint -183, -5, -256 and use the thin glass vial that's in your inventory. There are 2 vials in your inventory. Ensure you are using the correct vial.
Kill 10 Haflings under the overseers control. The Defiled Villagers in Enchanted Lands, as well as the Corrupted Halfings in Rivervale work. Dozens in Enchanted Lands at this location ( 425, 1, -593 ) Copy/waypoint 424.59, 0.73, -593.28.
Once all that is done, go into your inventory and use the rune adorned silver vial. You will now be given the Gift of Waking Dream. With that, head to Antonica and ( 137, -13, -191 ) Copy/waypoint 137, -13, -191. It's past the North Qeynos gates under the Aquaduct. Clicking the sewer-like entrance will zone you into the Tomb of the Seeress.
When you are inside, head straight forwards, up the steps and down the steps directly opposite. Be aware there are level 32, double down, aggro mobs in here. Thankfully they can all be solo'ed. Once on the other side, you will see the body of Seeress Ealaynya Ithis. Right-click her to give her the potion, and then hail the nice, new undead version! She will tell you why Rodcet Nife returned.
Now it's off to The Ruins of Varsoon (in The Thundering Steppes) to collect information. You can invis/stealth to these, but gathering the notes will break either of those abilities. They are in the following locations:
( -60, 4, 5 ) Copy/waypoint -60, 4, 5(Beware: Master Alchemist Pinjula spawns here, and can see through invisibility/stealth)
( 20, 0, 7 ) Copy/waypoint 20, 0, 7
( 72, 0, 36 ) Copy/waypoint 72, 0, 36
( 63, 0, 99 ) Copy/waypoint 63, 0, 99
Now you need to find evidence of Bertoxxulous in Norrath. What you're looking for here is mounds of dirt out in The Thundering Steppes. You will need to find 8 of these. They are found all over Thundering Steppes. Around RoV back door (5), near Qeynos Tower 1 and in Fallow Farmlands have proved successful. Found tons just out side the main entrance to The Ruins of Varsoon as well. They appear as a collectible dirt mound with green smoke above them (turning spell particles on helps a lot) Also, found 1 by heading back towards the SE griffon station and then around the crater to the left.
Once you have all of these, your next stop is Zek. Apparently, there are rumours of Bertoxxulous testing on orcs, so this is what you are sent to investigate. Just run around killing orcs for your update. You need 8 of them, and it appears to be uncommon, so this might take a while.