Fluffy may refer to any one of the following creatures in game:
- Fluffy, a cat in East Freeport
- Commander Fluffy, a cat in Qeynos Harbor
- !Fluffy, the Faux Enslaved Kobold in Steamfont Mountains that appears as part of Fulgation Sightings
- Fluffy (Dragon Entertainment)
- Fluffy (Fabled Dragon Entertainment)